EC Number |
Reaction |
Reference |
---|
3.5.3.1 | L-arginine + H2O = L-ornithine + urea |
also hydrolyses alpha-N-substituted L-arginines and canavanine |
654333 |
3.5.3.1 | L-arginine + H2O = L-ornithine + urea |
Asn130 and Ser137 are involved in substrate binding and catalysis |
654949 |
3.5.3.1 | L-arginine + H2O = L-ornithine + urea |
H141 as general acid to protonate the leaving amino group of L-ornithine during catalysis |
670673 |
3.5.3.1 | L-arginine + H2O = L-ornithine + urea |
H141 serves as an acid/base catalyst, deprotonating the metal-bridging water molecule to generate the metal-bridging hydroxide nucleophile, and by protonating the amino group of the product to facilitate its departure |
667319 |
3.5.3.1 | L-arginine + H2O = L-ornithine + urea |
hydrolysis via a metall-activated hydroxide mechanism, substrate binding structure |
654717 |
3.5.3.1 | L-arginine + H2O = L-ornithine + urea |
substrate binding structure |
654593 |
3.5.3.1 | L-arginine + H2O = L-ornithine + urea |
thermodynamic data |
172124 |