3.5.1.24 | glycocholate + H2O = cholate + glycine |
substrate specificity and active site structure, residues Cys1, Arg17, Asp20, Asn174, and Arg227 are important for catalysis, Trp21 plays a selective role in binding of bile salt while it suppresses productive binding of substrate analogue penicillin V |
669499 |