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3,12-dioxo-5beta-cholanoylglycine + H2O
3,12-dioxo-5beta-cholanate + Gly
-
-
-
-
?
3,12-dioxo-5beta-cholanoyltaurine + H2O
3,12-dioxo-5beta-cholanate + taurine
-
-
-
-
?
3,7-dioxo-5beta-cholanoylglycine + H2O
3,7-dioxo-5beta-cholanate + Gly
-
-
-
-
?
3,7-dioxo-5beta-cholanoyltaurine + H2O
3,7-dioxo-5beta-cholanate + taurine
-
-
-
-
?
3-oxo-5beta-cholanoylglycine + H2O
3-oxo-5beta-cholanate + Gly
-
-
-
-
?
3-oxo-5beta-cholanoyltaurine + H2O
3-oxo-5beta-cholanate + taurine
-
-
-
-
?
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oylglycine + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
-
-
-
-
?
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyltaurine + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
-
-
-
-
?
3alpha,7alpha,12alpha-trihydroxy-5beta-homocholan-24-oylglycine + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-homocholanate + glycine
-
-
-
-
?
3alpha,7alpha,12alpha-trihydroxy-5beta-homocholan-24-oyltaurine + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-homocholanate + taurine
-
-
-
-
?
3alpha,7alpha-dihydroxy-5beta-cholanoyl-alpha-aminomethanesulfonic acid + H2O
3alpha,7alpha-dihydroxy-5beta-cholanate + aminomethanesulfonic acid
-
-
-
-
?
3alpha,7alpha-dihydroxy-5beta-cholanoyl-beta-Ala + H2O
3alpha,7alpha-dihydroxy-5beta-cholanate + beta-Ala
-
-
-
-
?
3alpha,7alpha-dihydroxy-5beta-cholanoyl-DL-Ala + H2O
3alpha,7alpha-dihydroxy-5beta-cholanate + DL-Ala
-
-
-
-
?
3alpha,7alpha-dihydroxy-5beta-cholanoylsarcosine + H2O
3alpha,7alpha-dihydroxy-5beta-cholanate + sarcosine
-
low activity
-
-
?
3alpha,7alpha-dihydroxy-5beta-cholestan-26-oylglycine + H2O
3alpha,7alpha-dihydroxy-5beta-cholestanate + Gly
-
-
-
-
?
3alpha,7alpha-dihydroxy-5beta-cholestan-26-oyltaurine + H2O
3alpha,7alpha-dihydroxy-5beta-cholestanate + taurine
-
-
-
-
?
3alpha,7alpha-dihydroxy-5beta-homocholanoylglycine + H2O
3alpha,7alpha-dihydroxy-5beta-homocholanate + Gly
-
-
-
-
?
3alpha,7alpha-dihydroxy-5beta-homocholanoyltaurine + H2O
3alpha,7alpha-dihydroxy-5beta-homocholanate + taurine
-
-
-
-
?
3alpha,7beta-dihydroxy-5beta-cholanoylglycine + H2O
3alpha,7beta-dihydroxy-5beta-cholanate + Gly
-
-
-
-
?
3alpha,7beta-dihydroxy-5beta-cholanoyltaurine + H2O
3alpha,7beta-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
3alpha-hydroxy-12-oxo-5beta-cholanoylglycine + H2O
3alpha-hydroxy-12-oxo-5beta-cholanate + Gly
-
-
-
-
?
3alpha-hydroxy-12-oxo-5beta-cholanoyltaurine + H2O
3alpha-hydroxy-12-oxo-5beta-cholanate + taurine
-
-
-
-
?
3alpha-hydroxy-7-oxo-5beta-cholanylglycine + H2O
3alpha-hydroxy-7-oxo-5beta-cholanate + Gly
-
-
-
-
?
3alpha-hydroxy-7-oxo-5beta-cholanyltaurine + H2O
3alpha-hydroxy-7-oxo-5beta-cholanate + taurine
-
-
-
-
?
3beta,7alpha-dihydroxy-5beta-cholanoylglycine + H2O
3beta,7alpha-dihydroxy-5beta-cholanate + Gly
-
-
-
-
?
3beta,7alpha-dihydroxy-5beta-cholanoyltaurine + H2O
3beta,7alpha-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
3beta,7beta-dihydroxy-5beta-cholanoylglycine + H2O
3beta,7beta-dihydroxy-5beta-cholanate + Gly
-
-
-
-
?
3beta,7beta-dihydroxy-5beta-cholanoyltaurine + H2O
3beta,7beta-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
cholic acid + H2O
? + glycine
-
-
-
-
?
cholyl-alpha-aminomethanesulfonic acid + H2O
cholic acid + aminomethanesulfonic acid
-
-
-
-
?
cholyl-beta-Ala + H2O
cholic acid + beta-Ala
-
-
-
-
?
cholyl-DL-Ala + H2O
cholic acid + DL-Ala
-
-
-
-
?
cholylsarcosine + H2O
cholic acid + sarcosine
-
low activity
-
-
?
cholyltaurine + H2O
cholic acid + taurine
-
-
-
-
?
glyco-conjugated bile acid + H2O
?
-
-
-
-
?
glycochenodeoxycholate + H2O
glycine + chenodeoxycholate
glycochenodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + glycine
-
-
-
-
?
glycochenodeoxycholic acid + H2O
3alpha,7alpha-dihydroxy-5beta-cholanate + Gly
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
glycocholate + H2O
cholate + glycine
glycocholate + H2O
glycine + cholate
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + Gly
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
glycocholic acid + H2O
?
-
-
-
?
glycocholic acid + H2O
cholate + glycine
glycocholic acid + H2O
cholic acid + glycine
glycodeoxycholate + H2O
3alpha,12alpha-dihydroxy-5-beta-cholanate + glycine
-
-
-
-
?
glycodeoxycholate + H2O
glycine + deoxycholate
glycodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + Gly
glycodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + glycine
-
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
glycohyodeoxycholate + H2O
glycine + hyodeoxycholate
glycoursodeoxycholate + H2O
glycine + ursodeoxycholate
tauro-conjugated bile acid + H2O
?
-
-
-
-
?
taurochenodeoxycholate + H2O
chenodeoxycholate + taurin
taurochenodeoxycholate + H2O
taurine + chenodeoxycholate
taurochenodeoxycholic acid + H2O
3alpha,12alphadihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurochenodeoxycholic acid + H2O
3alpha,7alpha-dihydroxy-5beta-cholanate + taurine
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
taurocholate + H2O
taurine + cholate
taurocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
taurocholic acid + H2O
cholate + taurine
taurodeoxycholate + H2O
taurine + deoxycholate
taurodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + taurine
taurodeoxycholic acid + H2O
deoxycholate + taurine
taurodeoxycholic acid + H2O
taurine + deoxycholate
-
-
-
-
?
taurohyodeoxycholic acid + H2O
?
-
-
-
-
?
tauroursodeoxycholic acid + H2O
?
-
-
-
-
?
additional information
?
-
glycochenodeoxycholate + H2O

glycine + chenodeoxycholate
-
-
-
-
?
glycochenodeoxycholate + H2O
glycine + chenodeoxycholate
-
-
-
-
?
glycochenodeoxycholate + H2O
glycine + chenodeoxycholate
-
-
-
-
?
glycochenodeoxycholate + H2O
glycine + chenodeoxycholate
-
-
-
-
?
glycochenodeoxycholate + H2O
glycine + chenodeoxycholate
-
-
-
-
?
glycochenodeoxycholate + H2O
glycine + chenodeoxycholate
-
-
-
-
?
glycochenodeoxycholate + H2O
glycine + chenodeoxycholate
-
-
-
-
?
glycochenodeoxycholic acid + H2O

3alpha,7alpha-dihydroxy-5beta-cholanate + Gly
-
-
-
-
?
glycochenodeoxycholic acid + H2O
3alpha,7alpha-dihydroxy-5beta-cholanate + Gly
-
-
-
-
?
glycochenodeoxycholic acid + H2O
3alpha,7alpha-dihydroxy-5beta-cholanate + Gly
-
-
-
-
?
glycochenodeoxycholic acid + H2O
3alpha,7alpha-dihydroxy-5beta-cholanate + Gly
-
-
-
?
glycochenodeoxycholic acid + H2O

chenodeoxycholate + glycine
about 75% activity compared to glycocholic acid
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
about 75% activity compared to glycocholic acid
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
best substrate
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
best substrate
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
best substrate
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
best substrate
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
best substrate
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
-
-
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
-
-
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
-
-
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
J7H3P9
best substrate
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
-
-
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
J7H3P9
best substrate
-
-
?
glycocholate + H2O

cholate + glycine
preferred substrate
-
-
?
glycocholate + H2O
cholate + glycine
preferred substrate
-
-
?
glycocholate + H2O

glycine + cholate
-
-
-
-
?
glycocholate + H2O
glycine + cholate
-
-
-
-
?
glycocholate + H2O
glycine + cholate
-
-
-
-
?
glycocholate + H2O
glycine + cholate
-
-
-
-
?
glycocholate + H2O
glycine + cholate
-
-
-
-
?
glycocholate + H2O
glycine + cholate
-
-
-
?
glycocholate + H2O
glycine + cholate
-
-
-
-
?
glycocholate + H2O
glycine + cholate
-
-
-
-
?
glycocholic acid + H2O

3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + Gly
-
-
-
-
?
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + Gly
-
activity assay
-
-
?
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + Gly
-
-
-
?
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + Gly
-
activity assay
-
-
?
glycocholic acid + H2O

3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
100% activity
-
-
?
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
100% activity
-
-
?
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
-
-
-
-
?
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
-
-
-
-
?
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
-
-
-
-
?
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
-
strain CK102
-
-
?
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
-
-
-
-
?
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
-
-
-
-
?
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
-
-
-
-
?
glycocholic acid + H2O

cholate + glycine
-
-
-
?
glycocholic acid + H2O
cholate + glycine
-
-
-
?
glycocholic acid + H2O
cholate + glycine
-
-
-
-
?
glycocholic acid + H2O
cholate + glycine
J7H3P9
-
-
-
?
glycocholic acid + H2O
cholate + glycine
-
-
-
-
?
glycocholic acid + H2O

cholic acid + glycine
-
-
-
?
glycocholic acid + H2O
cholic acid + glycine
-
-
-
?
glycodeoxycholate + H2O

glycine + deoxycholate
-
-
-
-
?
glycodeoxycholate + H2O
glycine + deoxycholate
-
-
-
-
?
glycodeoxycholate + H2O
glycine + deoxycholate
-
-
-
-
?
glycodeoxycholate + H2O
glycine + deoxycholate
-
-
-
-
?
glycodeoxycholate + H2O
glycine + deoxycholate
-
-
-
-
?
glycodeoxycholate + H2O
glycine + deoxycholate
-
-
-
-
?
glycodeoxycholic acid + H2O

3alpha,12alpha-dihydroxy-5beta-cholanate + Gly
-
-
-
-
?
glycodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + Gly
-
-
-
-
?
glycodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + Gly
-
-
-
-
?
glycodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + Gly
-
-
-
-
?
glycodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + Gly
-
-
-
-
?
glycodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + Gly
-
-
-
-
?
glycodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + Gly
-
-
-
?
glycodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + Gly
-
-
-
-
?
glycodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + Gly
-
-
-
-
?
glycodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + Gly
-
-
-
-
?
glycodeoxycholic acid + H2O

deoxycholate + glycine
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
I3QNS9
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
about 80% activity compared to glycocholic acid
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
best substrate
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
best substrate
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
best substrate
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
best substrate
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
isoform BSH1 shows much higher hydrolysis on glycodeoxycholic acid than isoforms BSH2, BSH3 and BSH4
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
best substrate
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
best substrate
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
best substrate
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
best substrate
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
J7H3P9
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
J7H3P9
-
-
-
?
glycohyodeoxycholate + H2O

glycine + hyodeoxycholate
-
-
-
-
?
glycohyodeoxycholate + H2O
glycine + hyodeoxycholate
-
-
-
-
?
glycoursodeoxycholate + H2O

glycine + ursodeoxycholate
-
-
-
-
?
glycoursodeoxycholate + H2O
glycine + ursodeoxycholate
-
-
-
-
?
taurochenodeoxycholate + H2O

chenodeoxycholate + taurin
-
-
-
?
taurochenodeoxycholate + H2O
chenodeoxycholate + taurin
-
-
-
?
taurochenodeoxycholate + H2O
chenodeoxycholate + taurin
-
-
-
?
taurochenodeoxycholate + H2O
chenodeoxycholate + taurin
-
-
-
?
taurochenodeoxycholate + H2O
chenodeoxycholate + taurin
-
-
-
?
taurochenodeoxycholate + H2O
chenodeoxycholate + taurin
-
-
-
?
taurochenodeoxycholate + H2O

taurine + chenodeoxycholate
-
-
-
-
?
taurochenodeoxycholate + H2O
taurine + chenodeoxycholate
-
-
-
-
?
taurochenodeoxycholate + H2O
taurine + chenodeoxycholate
-
-
-
-
?
taurochenodeoxycholate + H2O
taurine + chenodeoxycholate
-
-
-
-
?
taurochenodeoxycholic acid + H2O

3alpha,7alpha-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurochenodeoxycholic acid + H2O
3alpha,7alpha-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurochenodeoxycholic acid + H2O
3alpha,7alpha-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurochenodeoxycholic acid + H2O
3alpha,7alpha-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurochenodeoxycholic acid + H2O
3alpha,7alpha-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurochenodeoxycholic acid + H2O

chenodeoxycholate + taurine
about 15% activity compared to glycocholic acid
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
about 15% activity compared to glycocholic acid
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
-
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
-
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
-
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
-
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
-
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
-
-
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
-
-
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
-
-
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
-
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
-
-
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
J7H3P9
-
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
-
-
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
J7H3P9
-
-
-
?
taurocholate + H2O

taurine + cholate
-
-
-
?
taurocholate + H2O
taurine + cholate
-
-
-
-
?
taurocholate + H2O
taurine + cholate
-
-
-
-
?
taurocholate + H2O
taurine + cholate
-
-
-
-
?
taurocholate + H2O
taurine + cholate
-
-
-
-
?
taurocholate + H2O
taurine + cholate
-
-
-
-
?
taurocholate + H2O
taurine + cholate
-
deconjugation
-
-
?
taurocholic acid + H2O

3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
about 20% activity compared to glycocholic acid
-
-
?
taurocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
about 20% activity compared to glycocholic acid
-
-
?
taurocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
-
hydrolyzing activity against tauroconjugated bile salts, but not glycoconjugated bile salts
-
-
?
taurocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
-
-
-
?
taurocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurocholic acid + H2O

cholate + taurine
-
-
-
?
taurocholic acid + H2O
cholate + taurine
-
-
-
?
taurocholic acid + H2O
cholate + taurine
-
-
-
-
?
taurocholic acid + H2O
cholate + taurine
J7H3P9
-
-
-
?
taurodeoxycholate + H2O

taurine + deoxycholate
-
-
-
-
?
taurodeoxycholate + H2O
taurine + deoxycholate
-
-
-
-
?
taurodeoxycholate + H2O
taurine + deoxycholate
-
-
-
-
?
taurodeoxycholate + H2O
taurine + deoxycholate
-
-
-
-
?
taurodeoxycholate + H2O
taurine + deoxycholate
-
-
-
-
?
taurodeoxycholate + H2O
taurine + deoxycholate
-
-
-
?
taurodeoxycholic acid + H2O

3alpha,12alpha-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O

deoxycholate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
I3QNS9
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
less than 20% activity compared to glycocholic acid
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
J7H3P9
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
J7H3P9
-
-
-
?
additional information

?
-
the enzyme exhibits clear preference for glycine-conjugated bile salts over taurine-conjugated forms
-
-
-
additional information
?
-
the enzyme exhibits clear preference for glycine-conjugated bile salts over taurine-conjugated forms
-
-
-
additional information
?
-
-
substrate specificity, overview
-
-
-
additional information
?
-
-
substrate specificity, overview
-
-
-
additional information
?
-
-
the enzyme catalyzes the deconjugation of glycine- or taurine-linked bile salts
-
-
-
additional information
?
-
-
substrate specificity profile, overview
-
-
-
additional information
?
-
-
BSH can hydrolyze all the six major human bile salts and at least two animal bile salts. BSH from five strains show a better deconjugation rate on glycine-conjugated bile salts than on taurine-conjugated forms
-
-
-
additional information
?
-
-
the SH group in the N-terminal cysteine is responsible for BSH activity, and amino acids, viz. Asp20, Tyr82, Asn175, and Arg228, are believed to take part actively along with Cys in catalysis of bile salts
-
-
-
additional information
?
-
substrate specificity of the purified enzyme, overview
-
-
-
additional information
?
-
-
substrate specificity of the purified enzyme, overview
-
-
-
additional information
?
-
substrate specificity of the purified enzyme, overview
-
-
-
additional information
?
-
substrate specificity of the purified enzyme, overview
-
-
-
additional information
?
-
-
substrate specificity, overview
-
-
-
additional information
?
-
-
substrate specificity, overview
-
-
-
additional information
?
-
-
substrate specificity of the purified enzyme, overview
-
-
-
additional information
?
-
substrate specificity of the purified enzyme, overview
-
-
-
additional information
?
-
substrate specificity of the purified enzyme, overview
-
-
-
additional information
?
-
substrate specificity of the purified enzyme, overview
-
-
-
additional information
?
-
-
catalyzes the hydrolysis of glycine- and taurine-conjugated bile salts to amino acid residues and free bile salts
-
-
-
additional information
?
-
-
the enzyme hydrolyzes all of the six major human bile salts
-
-
-
additional information
?
-
-
the enzyme contributes to the establishment of a successful infection through the oral route in mice, CGH confers the ability to the organism to resist the antimicrobial action of bile salts
-
-
-
additional information
?
-
the enzyme contributes to the establishment of a successful infection through the oral route in mice, CGH confers the ability to the organism to resist the antimicrobial action of bile salts
-
-
-
additional information
?
-
-
BSH catalyzes the hydrolysis of amide bond in conjugated bile salts and free amino acids are released, which form the deconjugated bile acid, mainly cholic and quenodeoxycholic
-
-
-
additional information
?
-
-
BSHs is highly substrate-specific, the two isozymes, encoded by two bsh genes, show different substrate specificities. BSHs can identify its substrate, bile acids, on amino acid groups, glycine/taurine, and also on cholate steroid nucleus. BSH recognizes the cholate group. The recombinant BSH from strain PF01 is active with tauroconjugated bile salts, but not with glycoconjugated bile slats
-
-
-
additional information
?
-
-
strain JCM1069 exhibits hydrolase activity against the taurodeoxycholic acid but not against the taurocholic acid, although both acids have taurine as their amino acid moiety but vary in their steroid moieties at 7alpha position
-
-
-
additional information
?
-
-
BSHs is highly substrate-specific and can identify its substrate, bile acids, on amino acid groups, glycine/taurine, and also on cholate steroid nucleus. BSH recognizes the cholate group. No activity with taurocholic acid
-
-
-
additional information
?
-
the recombinant enzyme hydrolyzes six major human bile salts with a slight preference towards glycine-conjugated bile salts, the enzyme shows a broad range of substrate specificity, overview. The enzyme also slightly prefers to hydrolyze conjugated cholates over conjugated deoxycholates and chenodeoxycholates
-
-
-
additional information
?
-
the recombinant enzyme hydrolyzes six major human bile salts with a slight preference towards glycine-conjugated bile salts, the enzyme shows a broad range of substrate specificity, overview. The enzyme also slightly prefers to hydrolyze conjugated cholates over conjugated deoxycholates and chenodeoxycholates
-
-
-
additional information
?
-
-
the recombinant enzyme hydrolyzes six major human bile salts with a slight preference towards glycine-conjugated bile salts, the enzyme shows a broad range of substrate specificity, overview. The enzyme also slightly prefers to hydrolyze conjugated cholates over conjugated deoxycholates and chenodeoxycholates
-
-
-
additional information
?
-
F7SGA1
isoyzme BSH A hydrolyses tauro-conjugated bile salts, whereas isozyme BSH C hydrolyses glycoconjugated bile salts. The enzymes have no preferential activities towards a specific cholyl moiety, the isozymes differ in their substrate specificities, overview
-
-
-
additional information
?
-
F7SGU2
isoyzme BSH A hydrolyses tauro-conjugated bile salts, whereas isozyme BSH C hydrolyses glycoconjugated bile salts. The enzymes have no preferential activities towards a specific cholyl moiety, the isozymes differ in their substrate specificities, overview
-
-
-
additional information
?
-
F7SHH3
isoyzme BSH A hydrolyses tauro-conjugated bile salts, whereas isozyme BSH C hydrolyses glycoconjugated bile salts. The enzymes have no preferential activities towards a specific cholyl moiety, the isozymes differ in their substrate specificities, overview
-
-
-
additional information
?
-
F7SGA1
isoyzme BSH A hydrolyses tauro-conjugated bile salts, whereas isozyme BSH C hydrolyses glycoconjugated bile salts. The enzymes have no preferential activities towards a specific cholyl moiety, the isozymes differ in their substrate specificities, overview
-
-
-
additional information
?
-
F7SGU2
isoyzme BSH A hydrolyses tauro-conjugated bile salts, whereas isozyme BSH C hydrolyses glycoconjugated bile salts. The enzymes have no preferential activities towards a specific cholyl moiety, the isozymes differ in their substrate specificities, overview
-
-
-
additional information
?
-
F7SHH3
isoyzme BSH A hydrolyses tauro-conjugated bile salts, whereas isozyme BSH C hydrolyses glycoconjugated bile salts. The enzymes have no preferential activities towards a specific cholyl moiety, the isozymes differ in their substrate specificities, overview
-
-
-
additional information
?
-
-
isoyzme BSH A hydrolyses tauro-conjugated bile salts, whereas isozyme BSH C hydrolyses glycoconjugated bile salts. The enzymes have no preferential activities towards a specific cholyl moiety, the isozymes differ in their substrate specificities, overview
-
-
-
additional information
?
-
-
BSHs BSHs is highly substrate-specific and can identify its substrate, bile acids, on amino acid groups, glycine/taurine, and also on cholate steroid nucleus. BSH recognizes the cholate group
-
-
-
additional information
?
-
-
isoform BSH1 prefers deoxycholic salts over chenodeoxycholic and cholic acid salts
-
-
-
additional information
?
-
-
the recombinant enzyme is more efficient in hydrolyzing glycoconjugated bile salts than tauroconjugated bile salts
-
-
-
additional information
?
-
-
the recombinant enzyme is more efficient in hydrolyzing glycoconjugated bile salts than tauroconjugated bile salts
-
-
-
additional information
?
-
-
isoform BSH1 prefers deoxycholic salts over chenodeoxycholic and cholic acid salts
-
-
-
additional information
?
-
J7H3P9
broad substrate specificity
-
-
-
additional information
?
-
-
broad substrate specificity
-
-
-
additional information
?
-
-
the Lactobacillus salivarius enzyme displays potent hydrolysis activity towards both glycoconjugated and tauroconjugated bile salts with broad substrate specificity
-
-
-
additional information
?
-
J7H3P9
broad substrate specificity
-
-
-
additional information
?
-
-
broad substrate specificity
-
-
-
additional information
?
-
-
the Lactobacillus salivarius enzyme displays potent hydrolysis activity towards both glycoconjugated and tauroconjugated bile salts with broad substrate specificity
-
-
-
additional information
?
-
-
oxgall is a substrate for the enzyme from different strains, overview
-
-
-
additional information
?
-
Lactobacillus spp.
-
enzyme activity is important for Lactobacillus colonization of human intestine
-
?
additional information
?
-
-
catalyzes the deconjugation of conjugated bile acids to liberate free primary bile acids and amino acids
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
cholic acid + H2O
? + glycine
-
-
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
glycocholate + H2O
cholate + glycine
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
glycocholic acid + H2O
cholate + glycine
J7H3P9
-
-
-
?
glycodeoxycholic acid + H2O
3alpha,12alpha-dihydroxy-5beta-cholanate + glycine
-
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
taurocholate + H2O
taurine + cholate
Q52UN2
-
-
-
?
taurocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
taurocholic acid + H2O
cholate + taurine
J7H3P9
-
-
-
?
taurodeoxycholate + H2O
taurine + deoxycholate
P54965
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
additional information
?
-
glycochenodeoxycholic acid + H2O

chenodeoxycholate + glycine
G0YYC2
about 75% activity compared to glycocholic acid
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
G0YYC2
about 75% activity compared to glycocholic acid
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
-
-
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
-
-
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
J7H3P9
best substrate
-
-
?
glycochenodeoxycholic acid + H2O
chenodeoxycholate + glycine
J7H3P9
best substrate
-
-
?
glycocholate + H2O

cholate + glycine
H6WSA2
preferred substrate
-
-
?
glycocholate + H2O
cholate + glycine
H6WSA2
preferred substrate
-
-
?
glycocholic acid + H2O

3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
G0YYC2
100% activity
-
-
?
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
G0YYC2
100% activity
-
-
?
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
-
-
-
-
?
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
-
strain CK102
-
-
?
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
-
-
-
-
?
glycocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine
-
-
-
-
?
glycodeoxycholic acid + H2O

deoxycholate + glycine
G0YYC2
about 80% activity compared to glycocholic acid
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
best substrate
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
best substrate
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
best substrate
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
best substrate
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
isoform BSH1 shows much higher hydrolysis on glycodeoxycholic acid than isoforms BSH2, BSH3 and BSH4
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
best substrate
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
best substrate
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
best substrate
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
-
best substrate
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
J7H3P9
-
-
-
?
glycodeoxycholic acid + H2O
deoxycholate + glycine
J7H3P9
-
-
-
?
taurochenodeoxycholic acid + H2O

chenodeoxycholate + taurine
G0YYC2
about 15% activity compared to glycocholic acid
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
G0YYC2
about 15% activity compared to glycocholic acid
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
-
-
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
-
-
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
J7H3P9
-
-
-
?
taurochenodeoxycholic acid + H2O
chenodeoxycholate + taurine
J7H3P9
-
-
-
?
taurocholic acid + H2O

3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
G0YYC2
about 20% activity compared to glycocholic acid
-
-
?
taurocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
G0YYC2
about 20% activity compared to glycocholic acid
-
-
?
taurocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurocholic acid + H2O
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O

deoxycholate + taurine
G0YYC2
less than 20% activity compared to glycocholic acid
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
-
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
J7H3P9
-
-
-
?
taurodeoxycholic acid + H2O
deoxycholate + taurine
J7H3P9
-
-
-
?
additional information

?
-
G0YYC2
the enzyme exhibits clear preference for glycine-conjugated bile salts over taurine-conjugated forms
-
-
-
additional information
?
-
G0YYC2
the enzyme exhibits clear preference for glycine-conjugated bile salts over taurine-conjugated forms
-
-
-
additional information
?
-
-
the enzyme catalyzes the deconjugation of glycine- or taurine-linked bile salts
-
-
-
additional information
?
-
-
BSH can hydrolyze all the six major human bile salts and at least two animal bile salts. BSH from five strains show a better deconjugation rate on glycine-conjugated bile salts than on taurine-conjugated forms
-
-
-
additional information
?
-
-
catalyzes the hydrolysis of glycine- and taurine-conjugated bile salts to amino acid residues and free bile salts
-
-
-
additional information
?
-
-
the enzyme hydrolyzes all of the six major human bile salts
-
-
-
additional information
?
-
-
the enzyme contributes to the establishment of a successful infection through the oral route in mice, CGH confers the ability to the organism to resist the antimicrobial action of bile salts
-
-
-
additional information
?
-
Q2YS20
the enzyme contributes to the establishment of a successful infection through the oral route in mice, CGH confers the ability to the organism to resist the antimicrobial action of bile salts
-
-
-
additional information
?
-
-
BSH catalyzes the hydrolysis of amide bond in conjugated bile salts and free amino acids are released, which form the deconjugated bile acid, mainly cholic and quenodeoxycholic
-
-
-
additional information
?
-
-
strain JCM1069 exhibits hydrolase activity against the taurodeoxycholic acid but not against the taurocholic acid, although both acids have taurine as their amino acid moiety but vary in their steroid moieties at 7alpha position
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-
-
additional information
?
-
-
isoform BSH1 prefers deoxycholic salts over chenodeoxycholic and cholic acid salts
-
-
-
additional information
?
-
-
isoform BSH1 prefers deoxycholic salts over chenodeoxycholic and cholic acid salts
-
-
-
additional information
?
-
-
oxgall is a substrate for the enzyme from different strains, overview
-
-
-
additional information
?
-
Lactobacillus spp.
-
enzyme activity is important for Lactobacillus colonization of human intestine
-
?
additional information
?
-
-
catalyzes the deconjugation of conjugated bile acids to liberate free primary bile acids and amino acids
-
-
-
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