EC Number   |
Application |
Reference |
|---|
   3.4.24.24 | diagnostics |
assessment of enzyme for monitoring and screening patients with prostate cancer. Significant correlation of densitometric analysis of enzyme activity and indirect hemagglutination titer, and prostate-specific antigen parameters |
669007 |
| 3.4.24.24 | diagnostics |
the MMP-2/TIMP-2 ratio may be of value in evaluating the prognosis in canine oronasal cavity tumors |
684054 |
| 3.4.24.24 | medicine |
attractive therapeutic target for cancer invasion and metastasis, morbidity and mortality of cancer patients are directly related to the ability of tumor cells to metastasize, gelatinase A is required by metastazing tumor cells to traverse basement membrane at tissue bounaries and in blood vessels, therefore this enzyme is a promising target for the development of antitumor drugs |
653757 |
| 3.4.24.24 | medicine |
during gastric ulcer healing, enzyme expression as well as matrix metalloproteinase MMP-3 and MMP-13 are induced in stromal cells of the gastric mucosa bordering the ulcer. Gelatinolytic activity is increased during the healing and is associated with extracellular matrix of the healing mucosa and newly formed vessels. Enzyme mRNA is homogenously distributed in all layers of the ulcer bed |
668382 |
| 3.4.24.24 | medicine |
endogenous urokinase plasminogen activator from cultured hepatic stellate cells significantly induces the active forms of enzyme and matrix metalloproteinase MMP-9 in cirrhotic tissue slices. Transfection of hepatic stellate cells with urokinase plasminogen activator gene results in overactivation of enzyme and matrix metalloproteinases MMP-3 and MMP-9 |
669677 |
| 3.4.24.24 | medicine |
enzyme is the main enzymatic activity of gelatinolysis in oral squamous cell carcinomas. The enzyme form/proform ratio obtained by zymography is significantly higher in T3 and T4 stages than in T1 and T2 stages |
669567 |
| 3.4.24.24 | medicine |
inhibitors for use as potential therapeutic agents |
652420 |
| 3.4.24.24 | medicine |
only a minority of urine samples from patients with bladder cancer show enzyme activity |
670449 |
| 3.4.24.24 | medicine |
ratio of matrx metalloproteinases MMP-9/MMP-2 is enhanced in cancer patients compared with benign diseases and healthy individuals. No correlation between gelatinolytic activity and high tumoral marker values is found |
668996 |
| 3.4.24.24 | medicine |
topical treatment of chronic dermal ulcers |
691260 |
