EC Number   |
Application |
Reference |
|---|
   3.4.14.9 | analysis |
development of fluorescence resonance energy transfer peptides using tryptophan as the fluorophore to study TPP-I hydrolytic properties. Assay can be applied to spleen and kidney homogenate |
754998 |
| 3.4.14.9 | diagnostics |
potential markers for Sjoegren's syndrome |
664615 |
| 3.4.14.9 | diagnostics |
saliva is a reliable and non-invasive source for the diagnosis of infantile (CLN1) and late infantile (CLN2) neuronal ceroid lipofuscinoses |
664616 |
| 3.4.14.9 | medicine |
adeno-associated virus 2-mediated CLN2 gene transfer to rodent and non-human primate brain results in long-term TPP-I expression compatible with therapy for late infantile neuronal ceroid lipofuscinosis |
665046 |
| 3.4.14.9 | medicine |
mutations in tripeptidyl-peptidase I underlie the classic late-infantile form of neuronal ceroid lipofuscinoses (CLN2), the most common neurodegenerative disorders of childhood |
678513 |
| 3.4.14.9 | medicine |
[Ala-Ala-Phe]2-rhodamine 110 and [Arg-Nle-Nle]2-rhodamine 110 are specific substrate for determining TPP-I activity and intracellular localization in living cells. These substrates can be a valuable tool for studying the neuronal pathology underlying classical late-infantile neuronal ceroid lipofuscinosis |
665906 |
| 3.4.14.9 | molecular biology |
fluorescent method for the histochemical detection of tripeptidyl peptidase I using glycyl-L-prolyl-L-Met-2-anthraquinonyl hydrazide as substrate |
664560 |
