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Literature summary for 3.4.14.9 extracted from

  • Steinfeld, R.; Fuhrmann, J.C.; Gaertner, J.
    Detection of tripeptidyl peptidase I activity in living cells by fluorogenic substrates (2006), J. Histochem. Cytochem., 54, 991-996.
    View publication on PubMed
Search for more literature for 3.4.14.9

Application

Application Comment Organism
medicine [Ala-Ala-Phe]2-rhodamine 110 and [Arg-Nle-Nle]2-rhodamine 110 are specific substrate for determining TPP-I activity and intracellular localization in living cells. These substrates can be a valuable tool for studying the neuronal pathology underlying classical late-infantile neuronal ceroid lipofuscinosis Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Homo sapiens 5764
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
neuron primary Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
[Ala-Ala-Phe]2-rhodamine 110 + H2O specific substrate for determining TPP-I activity and intracellular localization in living cells Homo sapiens [Ala-Ala-Phe]2 + rhodamine 110
-
 ?
[Arg-Nle-Nle]2-rhodamine 110 + H2O specific substrate for determining TPP-I activity and intracellular localization in living cells Homo sapiens [Ala-Ala-Phe]2 + rhodamine 110
-
 ?

Synonyms

Synonyms Comment Organism
TPP-I
-
 Homo sapiens