EC Number |
Application |
Reference |
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2.4.1.102 | diagnostics |
C2GnT1 might become a prognostic factor for endometrial carcinoma. Patients with C2GnT1 overexpression show significantly shorter survival, multivariable analysis also indicate that 2GnT1 overexpression is an independent prognostic factor |
736221 |
2.4.1.102 | diagnostics |
detection of core2 beta-1,6-N-acetylglucosaminyltransferase in post-digital rectal examination urine is a reliable indicator for extracapsular extension of prostate cancer. The number of GCNT1-positive cases is significantly lower in cases of organ-confined disease than in cases of extracapsular extension. GCNT1-negative tumors are a associated with significantly better prostate-specific antigen (PSA)-free survival compared with GCNT1-positive tumors. Multivariate analysis reveals that detection of GCNT1 expression is an independent risk factor for prostate-specific antigen recurrence |
737091 |
2.4.1.102 | diagnostics |
GCNT1 expression in prostate biopsy specimen is a significant and independent predictor of recurrence after radical prostatectomy, which can be used in pre-treatment decision making for the patient |
735617 |
2.4.1.102 | diagnostics |
GCNT3 might be an essential glycosylation-related molecule in colorectal cancer and epithelial ovarian cancer progression, with potential interest as a predictive biomarker of response to chemotherapy. GCNT3 high-expressing Stage III-IV EOC patients have better response to conventional treatment and clinical outcome. Clinical relevance of GCNT3 expression in epithelial ovarian cancer (EOC), role of GCNT3 as a biomarker for cancer patients, overview |
760171 |
2.4.1.102 | diagnostics |
possible role of GCNT3 gene expression as prognostic marker in colon cancer. Low CNT3 expression is a promising prognostic biomarker for colon cancer that could be used to identify early-stage colon cancer patients at high risk of relapse. The enzyme might also constitute a biomarker to monitor tumour response to chemotherapy in cancer patients |
736047 |
2.4.1.102 | medicine |
biomarker for aggressive potential of testicular germ cell tumor |
704080 |
2.4.1.102 | medicine |
C2GnT-1 may be a candidate of therapeutic target for the inhibition of infiltration of leukemia cells |
675735 |
2.4.1.102 | medicine |
clinical relevance of the differential expression of the glycosyltransferase gene GCNT3 in colon cancer, clinicopathological parameters, overview |
736047 |
2.4.1.102 | medicine |
core2GnT is an extremely useful prognostic marker for prostate cancer progression |
673873 |
2.4.1.102 | medicine |
GCNT1 expression in prostate biopsy specimen is a significant and independent predictor of recurrence after radical prostatectomy, which can be used in pre-treatment decision making for the patient |
735617 |