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Literature summary for 2.4.1.102 extracted from
- Transfection of antisense core 2 beta1,6-N-acetylglucosaminyltransferase-1 cDNA suppresses selectin ligand expression and tissue infiltration of B-cell precursor leukemia cells (2005), Leukemia, 19, 1934-1940.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | C2GnT-1 may be a candidate of therapeutic target for the inhibition of infiltration of leukemia cells | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | C2GnT-1 regulates selectin ligand expression. Downregulation of the selectin ligand expression level inhibits tissue infiltration of BCP-leukemia cells | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | C2GnT-1 regulates selectin ligand expression. Downregulation of the selectin ligand expression level inhibits tissue infiltration of BCP-leukemia cells | Homo sapiens | ? | - |
? | |
| UDP-N-acetyl-D-glucosamine + Galbeta1,3GalNAcalpha1-p-nitrophenyl | - |
Homo sapiens | ? | - |
? | |
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