EC Number   |
Application |
Reference |
|---|
    2.3.1.51 | medicine |
expression of isoform AGPAT11 mRNA is signifi cantly upregulated in human breast, cervical, and colorectal cancer tissues |
720175 |
| 2.3.1.51 | medicine |
expression of isoform CGI-58 in fibroblasts from humans with Chanarin-Dorfman increases the incorporation of fatty acids released from the lipolysis of stored triacylglycerols into phospholipids |
705011 |
| 2.3.1.51 | medicine |
expression of isoform LPAATbeta is readily detected in 8 of 10 analyzed human osteosarcoma lines. Exogenous expression of LPAATbeta promotes osteosarcoma cell proliferation and migration, while silencing LPAATbeta expression inhibits these cellular characteristics. Exogenous expression of LPAATbeta effectively promotes tumor growth, while knockdown of LPAATbeta expression inhibits tumor growth in an orthotopic xenograft model of human osteosarcoma |
720813 |
| 2.3.1.51 | medicine |
the role of isoforms AGPAT1 or AGPAT2 in liver lipogenesis is minimal and accumulation of liver fat is primarily a consequence of insulin resistance and loss of adipose tissue in Agpat2 -/- mice |
719977 |
