EC Number   |
Application |
Reference |
|---|
   1.4.1.3 | analysis |
development of a glutamate amperometric sol-gel biosensor. A carbon paste electrode is electrochemically modified with methylene green. NADP+ and glutamate dehydrogenase are coimmobilised in a sol-gel matrix. When coupled to a flow injection system, the biosensor shosd good electrocatalytic activity towards NADPH oxidation at a potential of + 0.3 V vs. Ag/AgCl. The biosensor yields a linear response from 50 microM to 10 mM glutamate, with a detection limit of 5 microM and reproducibility of results better than 2.3% |
742758 |
| 1.4.1.3 | analysis |
simple and reliable staining procedure to detect GDH activity in plant tissues that can be used, with different purposes, to determine GDH expression in plant organs, tissues, extracts and also heterologous systems. The staining solution consists of Tris-HCl (pH 8.8), sodium glutamate, NAD, phenazine methosulfate and Nitro Blue Tetrazolium |
763596 |
| 1.4.1.3 | medicine |
by regulating bioenergetics and redox homeostasis human GDH1/2 have emerged as key players in the pathogenesis of human neoplasias and as therapeutic targets for halting tumor development and expansion |
762783 |
| 1.4.1.3 | medicine |
serum GLDH activity is an ideal marker of alcoholism since it is elevated in alcohol abuse but its activity declines promptly after the last alcohol intake |
684262 |
| 1.4.1.3 | more |
C323 plays an important role in catalysis by human GDH isozymes |
675933 |
| 1.4.1.3 | nutrition |
restricted feeding with food access for 2 h each day for three weeks promotes higher levels of mitochondrial glutamate dehydrogenase protein and activity, as well as a loss of 24-h rhythmicity, in comparison to ad libitum conditions. The rhythmicity of glutamate dehydrogenase activity detected in serum is changed |
742455 |
