EC Number   |
Application |
Reference |
|---|
   1.2.1.36 | degradation |
ALDH1A1 appears to be the major if not the only enzyme responsible for the oxidation of 3-deoxyglucosone to 2-keto-3-deoxygluconate |
691121 |
| 1.2.1.36 | degradation |
urinary excretion of 2-keto-3-deoxygluconate amounts to 16.7 micromol/g creatinine in humans, indicating that 3-deoxyglucosone may be quantitatively a more important substrate than retinaldehyde for ALDH1A1 |
691121 |
| 1.2.1.36 | diagnostics |
ALDH1A1 is rapidly gaining importance as a stem cell marker |
743375 |
| 1.2.1.36 | medicine |
activity of any one isoform is not rate limiting in the visual response |
694144 |
| 1.2.1.36 | medicine |
low retinal dehydrogenase 5 expression is associated with metastasis and poor patient prognosis |
763150 |
| 1.2.1.36 | medicine |
RALDH1 is a negative regulator of allergic inflammation |
700363 |
| 1.2.1.36 | medicine |
retinoic acid down-regulates aldehyde dehydrogenase and increases cytotoxicity of 4-hydroperoxycyclophosphamide and acetaldehyde in lung cancer cell lines |
656611 |
| 1.2.1.36 | molecular biology |
ALDH1A1 is rapidly gaining importance as a stem cell marker |
743375 |
| 1.2.1.36 | more |
Raldh3 is a zebrafish ortholog of mammalian Raldh3. The predicted protein encoded by zebrafish raldh3 exhibits 70.0% amino acid identity with mouse Raldh3 |
692481 |
| 1.2.1.36 | more |
Raldh4 is a zebrafish ortholog of mammalian Raldh4. The predicted protein encoded by zebrafish raldh4 exhibits 73.5% amino acid identity with mouse Raldh4 |
692481 |
