EC Number   |
Application |
Reference |
|---|
    3.2.1.51 | medicine |
deficiency in enzyme activity is associated with fucosidosis |
656203 |
| 3.2.1.51 | medicine |
gastric cancer cells infected with Helicobacter pylori secrete isoform Fuc2A. Fuc2A is essential for Helicobacter pylori adhesion, in particular to the gastric cancer- and duodenal ulcer-specific strains. FUCA2 significantly enhances the expression of Lewis x antigen in Helicobacter pylori, which is critical for bacterial cell adhesion in the pathogenesis and defense strategy to escape host surveillance |
710413 |
| 3.2.1.51 | medicine |
has a role in the intimate species signature interactions between sperm and oocyte. Relevance for reproductive function in nature or in assisted reproductive technologies |
682040 |
| 3.2.1.51 | medicine |
may be useful as a biomarker for predicting the progression-free survival of for trastuzumab treatment |
699825 |
| 3.2.1.51 | medicine |
progression-free survival significantly longer in high FUCA activity group than in low FUCA activity group, not correlated to clinical response to trastuzumab but maybe useful as biomarker for predicting progression-free survival for trastuzumab treatment, serum FUCA activity correlates with early detection in hepatocellular carcinoma |
699825 |
| 3.2.1.51 | medicine |
quality of semen is affected in part by the loss in the activity of alpha-fucosidase, which may be useful in early diagnosis of the loss in reproductive capacity during the course of trypanosomiasis and fertility tests |
680897 |
| 3.2.1.51 | medicine |
recombinant enzyme will extend the proven efficiacy of enzyme replacement therapy in lysosomal storage disorders e.g. fucosidosis |
208694 |
| 3.2.1.51 | medicine |
the differentiation of HT-29 colon cancer cells can be used as a model to study the alteration of the enzyme alpha-L-fucosidase during the progression of the tumoural processs |
655733 |
| 3.2.1.51 | medicine |
the enzyme is an indicator of poor prognosis for patients with advanced-stage triple-negative breast cancer |
739213 |
| 3.2.1.51 | synthesis |
the transfucosylation ability of one of the fucosidase isoform might be of interest for the synthesis of fucosides |
-, 750710 |
