EC Number |
Natural Substrates |
---|
5.6.1.2 | ATP + H2O + a dynein associated with a microtubule at position n |
- |
5.6.1.2 | ATP + H2O + a dynein associated with a microtubule at position n |
cytoplasmic dynein heavy chain 2.2 is required for flagellar assembly and also participates in maintenance of promastigote cell shape. LmxDHC2.2 is not an essential gene |
5.6.1.2 | ATP + H2O + a dynein associated with a microtubule at position n |
cytoplasmic dynein is an AAA+ motor responsible for intracellular cargo transport and force generation along microtubules |
5.6.1.2 | ATP + H2O + a dynein associated with a microtubule at position n |
cytoplasmic dynein is the sole motor for microtubule-based ER motility throughout the early stages of development |
5.6.1.2 | more |
cytoplasmic dynein may play structural and functional roles in the postsynaptic terminal |
5.6.1.2 | ATP + H2O + a dynein associated with a microtubule at position n |
dynactin and cytoplasmic dynein require each other for microtubule plus-end accumulation. The presence of cytoplasmic dynein is also important for the microtubule plus-end accumulation of NADF |
5.6.1.2 | ATP + H2O + a dynein associated with a microtubule at position n |
dynein has a dominant function in transporting kinetochore microtubule bundles (K fibers) to the centrosomes |
5.6.1.2 | more |
dynein intermediate chain isoforms define dynein populations that are selectively recruited to transport distinct cargoes. Neurotrophin receptor tyrosine kinase B signaling endosomes are transported by cytoplasmic dynein containing the neuron-specific intermediate chain-1B isoform and not by dynein containing the ubiquitous intermediate chain-2C isoform. Organelles containing tyrosine kinase B also contain dynein with intermediate chain-1 but not intermediate chain-2 isoforms |
5.6.1.2 | ATP + H2O + a dynein associated with a microtubule at position n |
dynein is a motor protein that moves on microtubules using the energy of adenosine triphosphate hydrolysis |
5.6.1.2 | ATP + H2O + a dynein associated with a microtubule at position n |
dynein is a primary motor for fast transport of mitochondria in Drosophila motor axons |