EC Number |
Natural Substrates |
---|
2.7.8.3 | cytidine diphosphate choline + N-acyl-threo-trans-sphingosine |
- |
2.7.8.3 | cytidine diphosphate choline + N-acyl-threo-trans-sphingosine |
sphingomyelin is synthesized predominantly via direct transfer of the phosphorylcholine group from phosphatidylcholine, synthesis of sphingomyelin by the action of CDPcholine:ceramide cholinephosphotransferase occurs only to an extent of 2% in vivo |
2.7.8.3 | cytidine diphosphate choline + N-acyl-threo-trans-sphingosine |
biosynthetic pathway of sphingomyelin |
2.7.8.3 | cytidine diphosphate choline + N-acyl-threo-trans-sphingosine |
sphingomyelin metabolism |
2.7.8.3 | cytidine diphosphate choline + N-acyl-threo-trans-sphingosine |
in vivo the proximal donor of the phosphocholine moiety of sphingomyelin is not CDPcholine but most probably phosphatidylcholine |