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EC Number	Natural Substrates	Commentary (Nat. Sub.)
2.5.1.118	O3-acetyl-L-serine + isoxazolin-5-one	the enzyme also forms 3-(5-oxoisoxazolin-4-yl)-L-alanine in vitro (cf. EC 2.5.1.119). Only 3-(5-oxoisoxazolin-2-yl)-L-alanine is formed in vivo. 3-(5-oxoisoxazolin-2-yl)-L-alanine is the biosynthetic precursor of the neurotoxin N3-oxalyl-L-2,3-diaminopropanoic acid, the cause of lathyrism

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Release 2023.1 (January 2023)