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Results 1 - 8 of 8

EC Number	Natural Substrates	Commentary (Nat. Sub.)
2.4.2.64	guanine34 in tRNA + queuine	-
2.4.2.64	guanine34 in tRNA + queuine	catalyses a base-exchange reaction that leads to anticodon modifications of certain tRNAs
2.4.2.64	guanine34 in tRNA + queuine	the enzyme is responsible for the formation of queuosine in the anticodon loop (position 34) of tRNAAsp, tRNAAsn, tRNAHis, and tRNATyr
2.4.2.64	more	-
2.4.2.64	more	key enzyme involved in the incorporation of the modified base queuine into tRNA
2.4.2.64	more	higher expression of the subunit TGT60KD in cancer cells than in normal cells. The expression levels of the TGT60KD subunit regulate enzyme activity and the level of queuosine. TGT60KD plays significant roles in carcinogenesis
2.4.2.64	more	the enzyme is required for virulence
2.4.2.64	more	the 60000 Da subunit of the enzyme plays a role in colon carcinogenesis

Results 1 - 8 of 8

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Release 2023.1 (January 2023)