EC Number |
Recommended Name |
Natural Substrates |
Organism |
Natural Products |
Reversibility |
---|
2.4.1.255 | protein O-GlcNAc transferase |
more |
Homo sapiens |
catalyzes the transfer of O-linked GlcNAc to serine or threonine residues of a variety of substrate proteins, including nuclear pore proteins, transcription factors, and proteins implicated in diabetes and neurodegenerative disorders |
? |
- |
? |
2.4.1.255 | protein O-GlcNAc transferase |
more |
Homo sapiens |
catalyzes the transfer of O-linked GlcNAc to serine/threonine residues of a variety of target proteins, many of which have been implicated in such diseases as diabetes and neurodegeneration |
? |
- |
? |
2.4.1.255 | protein O-GlcNAc transferase |
more |
Homo sapiens |
enzyme transfers N-acetylglucosamine from UDP-GlcNAc to selected serine and threonine residues |
? |
- |
? |
2.4.1.255 | protein O-GlcNAc transferase |
more |
Homo sapiens |
regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1 |
? |
- |
? |
2.4.1.255 | protein O-GlcNAc transferase |
more |
Homo sapiens |
regulation of O-GlcN acylation over a broad range of glucose concentrations, significant induction of O-GlcNAc modification of a limited number of proteins under conditions of glucose deprivation |
? |
- |
? |
2.4.1.255 | protein O-GlcNAc transferase |
more |
Homo sapiens |
transfer of O-linked GlcNAc to serine/threonine residues of a variety of substrate proteins, including nuclear pore proteins, transcription factors, and proteins implicated in diabetes and neurodegenerative disorders |
? |
- |
? |
2.4.1.255 | protein O-GlcNAc transferase |
more |
Homo sapiens |
enzyme adds a single GlcNAc to hydroxyl groups of serine and threonine residues. Substrates are many proteins, e.g. transcription factors, kinases, cytoskeletal proteins, and nuclear pore proteins |
? |
- |
? |
2.4.1.255 | protein O-GlcNAc transferase |
more |
Homo sapiens |
enzyme catalyzes O-GlcNAc addition |
? |
- |
? |
2.4.1.255 | protein O-GlcNAc transferase |
more |
Homo sapiens |
enzyme catalyzes the addition of O-GlcNAc moieties to nuclear and cytoplasmic proteins at serine and threonine residues, regulates some aspects of mitotic chromatin dynamics. OGT protein amounts decrease during M phase |
? |
- |
? |
2.4.1.255 | protein O-GlcNAc transferase |
more |
Homo sapiens |
enzyme is a key molecule for the timely progression of the cell cycle. Microinject recombinant proteins into oocytes to detail the relationship between cell cycle and O-GlcNAc |
? |
- |
? |