EC Number |
Natural Substrates |
---|
2.4.1.149 | UDP-N-acetyl-alpha-D-glucosamine + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R |
- |
2.4.1.149 | UDP-N-acetyl-D-glucosamine + poly-N-acetyllactosamine |
- |
2.4.1.149 | more |
B3gnt1 null females are fertile, the B3gnt1 null males are not able to sire litters at the expected rate when mated to either wild type or B3gnt1-null females |
2.4.1.149 | more |
beta3GnT7 may play a role in preventing cells from migrating out of the original tissues and invading surrounding tissues |
2.4.1.149 | more |
biosynthesis of Ii core glycosphingolipids |
2.4.1.149 | more |
biosynthesis of lacto-series core chains, enzyme is activated in association with oncogenesis in colonic epithelia |
2.4.1.149 | UDP-N-acetyl-D-glucosamine + poly-N-acetyllactosamine |
biosynthesis of poly-N-acetyllactosamine chains on N-linked oligosaccharides, catalyzes a rate-limiting reaction in the expression of poly-N-acetyllactosamine chains, especially in pheochromocytoma cells |
2.4.1.149 | UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R |
enzyme functions in both the initiation and elongation of linear i-active polylactosaminoglycan chains of N-glycoproteins and possibly other glycoconjugates |
2.4.1.149 | UDP-N-acetyl-D-glucosamine + poly-N-acetyllactosamine |
enzyme is capable of elongation of polylactosamine i-chains |
2.4.1.149 | UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R |
enzyme is essential for the formation of poly-N-acetyllactosamines and the i-antigen, responsible for the formation of GlcNAcbeta(1-3)Galbeta(1-4)GlcNAc-R structure and poly-N-acetyllactosamine extension |