EC Number   |
Natural Substrates |
|---|
    2.1.2.5 | 5-formimidoyltetrahydrofolate + L-glutamate |
- |
| 2.1.2.5 | N-formiminoglutamate + tetrahydrofolate |
bifunctional formiminotransferase cyclodeaminase, 58K, is associated with the cytoplasmatic surface of the Golgi apparatus in vivo |
| 2.1.2.5 | N-formiminoglutamate + tetrahydrofolate |
metabolic enzyme involved in the conversion of histidine to glutamic acid |
| 2.1.2.5 | N-formiminoglutamate + tetrahydrofolate |
in addition to its enzymatic activity enzyme may have a second physiological function in mediating interaction of Golgi-derived membranes with microtubules |
| 2.1.2.5 | N-formiminoglutamate + tetrahydrofolate |
physiological substrate is (6S)-tetrahydrofolate |
| 2.1.2.5 | N-formiminoglutamate + tetrahydrofolate |
enzyme serves as additional entry point for the folate pool in liver |
| 2.1.2.5 | N-formiminoglutamate + tetrahydrofolate |
histidine metabolism pathway, reaction occurs in vivo within the soluble phase of cytoplasm |
| 2.1.2.5 | N-formiminoglutamate + tetrahydrofolate |
histidine degradation |
| 2.1.2.5 | tetrahydrofolate + N-formimidoyl-L-glutamate |
FTCD in the centrosome may be associated with polyglutamylated residues of centriole microtubules and may play a role in providing centrioles with glutamate produced by cyclodeaminase domains of FTCD |
