EC Number |
Natural Substrates |
---|
1.1.1.159 | 7-keto-lithocholic acid + NADH |
in the gastrointestinal tract of host organisms |
1.1.1.159 | bile acids + NAD(P)+ |
- |
1.1.1.159 | bile acids + NAD(P)+ |
dehydrogenation of hydroxyl group at position 7, wide variety of substrate binding specificities in short-chain dehydrogenase enzyme family |
1.1.1.159 | bile acids + NAD(P)+ |
serve as energy sources in absence of glucose |
1.1.1.159 | cholate + NAD+ |
- |
1.1.1.159 | more |
bile acid-induction, e.g. deoxycholate and chenodeoxycholate, is necessary for measurable activity, induction is inhibited by ursodeoxycholate |
1.1.1.159 | more |
cholic acid inducible |
1.1.1.159 | more |
bile acid-inducible to 10fold higher activity on substrate compared to uninduced cells |
1.1.1.159 | more |
substrate specificity and cycles in bile acid pathways, overview |
1.1.1.159 | taurochenodeoxycholic acid + NADP+ |
- |