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Information on EC 1.1.1.159 - 7alpha-hydroxysteroid dehydrogenase

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IUBMB Comments
Catalyses the oxidation of the 7alpha-hydroxy group of bile acids and alcohols both in their free and conjugated forms. The Bacteroides fragilis and Clostridium enzymes can also utilize NADP+.
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The enzyme appears in viruses and cellular organisms
Synonyms
7alpha-hsdh, 7alpha-hsd, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
cholate + NAD+ = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholan-24-oate + NADH + H+
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