EC Number |
Natural Substrates |
---|
2.3.1.48 | 4 acetyl-CoA + histone H4 |
- |
2.3.1.48 | acetyl-CoA + beta-site amyloid precursor protein-cleaving enzyme 1 |
- |
2.3.1.48 | acetyl-CoA + c-Myc |
acetylation by Tip60 increases c-Myc protein stability in transfected H-1299 human lung carcinoma cells |
2.3.1.48 | acetyl-CoA + histone |
- |
2.3.1.48 | acetyl-CoA + histone |
histone H1 is not acetylated in vivo |
2.3.1.48 | acetyl-CoA + histone |
Esa1 protein is involved in cell cycle regulation |
2.3.1.48 | acetyl-CoA + histone |
involved in chromatin remodeling and DNA repair |
2.3.1.48 | acetyl-CoA + histone |
histone H3 is the preferred substrate |
2.3.1.48 | acetyl-CoA + histone |
neutralization of positively charged lysine residues by acetylation lowering the affinity of histone octamers for the negatively charged DNA |
2.3.1.48 | acetyl-CoA + histone |
involved in dynamic equilibrium of core histone acetylation |