EC Number   |
Natural Substrates |
|---|
   4.1.99.3 | more |
CPD photolyase, which rapidly repairs CPDs, is essential for plant survival under sunlight containing UVB |
| 4.1.99.3 | more |
CPDs and 6-4PPs play different roles in UV-induced cell death in normal and NER-deficient human cells |
| 4.1.99.3 | more |
CryA can repair DNA upon exposure to UVA light similar to other photolyase proteins, CryA represses sexual development under UVA350-370 nm light and exhibits a regulatory function during light-dependent development and DNA repair activity, in the wild type strain mechanisms such as excision repair mask the DNA photolyase activity of CryA |
| 4.1.99.3 | more |
pre-inoculation UV-C (254 nm) treatment of normally susceptible Arabidopsis thaliana accessions induces prolonged, dose-dependent resistance to virulent isolates of the phytopathogenic oomycete Hyaloperonospora parasitica with cyclobutane pyrimidine dimers and (6-4) photoproducts playing a key role in this response |
| 4.1.99.3 | more |
the native rice CPD photolyase is phosphorylated, whereas the Escherichia coli-expressed rice CPD photolyase is not |
| 4.1.99.3 | more |
PHR1 and PHR2 are able to bind the CLOCK protein, a transcription activator controlling the molecular circadian clock. But only for PHR2, the physical interaction with CLOCK represses CLOCK/BMAL1-driven transcription, binding of photolyase per se is not sufficient to inhibit the CLOCK/BMAL1 heterodimer |
| 4.1.99.3 | more |
PhrB does not function as a photolyase |
| 4.1.99.3 | more |
the enzyme has blue light photoreceptor activity and CPD photolyase activity. Signaling might be mediated by the PHR besides its effects on the C-terminal extension, conformational changes in cryptochromes upon illumination, overview |
