EC Number   |
Natural Substrates |
|---|
    2.7.4.3 | more |
adenylate kinase is involved in the control of the rate of glycolysis |
| 2.7.4.3 | more |
adenylate kinase participates in the regulation of ADP-dependent endocytosis of high-density lipoprotein by consuming the ADP generated by the ecto-F1-ATPase |
| 2.7.4.3 | more |
adenylate kinase activity of the Mre11/Rad50 complex, which is part of a DNA repair complex, promotes DNA-DNA associations |
| 2.7.4.3 | more |
adenylte kinase-catalysed ADP production in the vicinity of K/ATP channels is involved in channel regulation |
| 2.7.4.3 | more |
interaction between mitochondrial adenylate kinase and nucleoside diphosphate kinase. Adenylate kinase stimulates nucleoside diphosphate kinase activity, whereas nucleoside diphosphate kinase inhibits adenylate kinase activity. the net effect may be unchanged ADP production albeit with different rates of substrate consumption |
| 2.7.4.3 | more |
Rad50 adenylate kinase activity is required for DNA tethering |
| 2.7.4.3 | more |
secretion of adenylate kinase 1 is required for extracellular ATP synthesis in myotubes |
| 2.7.4.3 | more |
the cystic fibrosis transmembrane conductance regulator (CFTR) has adenylate kinase activity as an ABC adenylate kinase. ATP enables CFTR photolabeling by 8-N3-AMP, and AMP increases 8-N3-ATP photolabeling at ATP-binding site 2. AMP interacts with CFTR in an ATP-dependent manner and alters ATP interaction with the adenylate kinase active center ATP-binding site. Two other ABC proteins, Rad50 and a structural maintenance of chromosome protein, also have adenylate kinase activity. All three ABC adenylate kinases bind and hydrolyze ATP in the absence of other nucleotides |
