EC Number |
Natural Substrates |
---|
2.7.1.189 | ATP + 1,2-dihydroxyoctane-3,4-dione |
- |
2.7.1.189 | ATP + 1,2-dihydroxyundecane-3,4-dione |
- |
2.7.1.189 | ATP + 1-cyclopropyl-3,4-dihydroxybutane-1,2-dione |
- |
2.7.1.189 | ATP + 4,5-dihydroxypentane-2,3-dione |
- |
2.7.1.189 | ATP + 4,5-dihydroxypentane-2,3-dione |
the kinase LsrK phosphorylates carbon-5 of the open form of the substrate, molecule (S)-4,5-dihydroxypentane-2,3-dione is the precursor of the signal molecule autoinducer-2 |
2.7.1.189 | ATP + autoinducer-2 |
- |
2.7.1.189 | ATP + autoinducer-2 |
i.e. AI-2 |
2.7.1.189 | more |
no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview |
2.7.1.189 | more |
the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 |