EC Number   |
Natural Substrates |
|---|
    2.3.1.180 | more |
the enzyme prefers short-chain CoA primer substrates |
| 2.3.1.180 | more |
the wild-type enzyme is able to induce synthesis of polyhydroxyalkanoates PHA copolymers from glucose in a strain which is transformed with gene phaC from Aeromonas caviae or gene phaC1 from Pseudomonas sp. strain 61-3, thus fatty acid biosynthesis may supply monomers for PHA production, overview |
| 2.3.1.180 | more |
beta-ketoacyl-acyl carrier protein synthase III, FabH, carries out first the first condensation reaction in fatty acid biosynthesis, which determines the type of fatty acid produced in bacteria |
| 2.3.1.180 | more |
FabH catalyzes the initial step of fatty acid biosynthesis via a type II fatty acid synthase, FabH has an important role as essential enzyme combined with unique structural features and ubiquitous occurrence |
| 2.3.1.180 | more |
FabH is regulated by Ser/Thr protein kinase-dependent phosphorylation at Thr45, overview |
| 2.3.1.180 | myristoyl-CoA + malonyl-[acyl-carrier protein] |
the enzyme plays a key role in initiation of the long-chain fatty acid route of meromycolic acid biosynthesis, a different enzyme with specificity for short-chain acyl-CoAs might also be responsible for meromycolic acid biosynthesis, biosynthetic pathway regulation mechanism |
| 2.3.1.180 | propionyl-CoA + malonyl-[acyl-carrier protein] |
the enzyme specifies the propionate-starter unit for type II polyketide biosynthesis |
