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Results 31 - 33 of 33

EC Number	Natural Substrates	Commentary (Nat. Sub.)
1.14.15.18	more	the enzyme is involved in local production of 1alpha,25-dihydroxyvitamin D, i.e. 1alpha,25(OH)2D3, in tumorigenesis
1.14.15.18	more	the 1alpha-OHase gene is a tumor suppressor gene responsible for the normal regulation of prostate cell growth
1.14.15.18	more	Vdh, a cytochrome P450 enzyme, is responsible for the biocatalytic conversion of vitamin D3, catalyzing the two-step hydroxylation of VD3, i.e. the conversion of VD3 to 25-hydroxyvitamin D3 (25(OH)VD3) and then of 25(OH)VD3 to 1alpha,25(OH)2VD3, a hormonal form of VD3. Anti-parallel substrate binding modes enable sequential hydroxylation, structure-function analysis, overview

Results 31 - 33 of 33

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Release 2023.1 (January 2023)