EC Number |
Metals/Ions |
Reference |
---|
5.3.4.1 | Ag+ |
PDI binds Ag+ |
649629 |
5.3.4.1 | Ca2+ |
1-5 mM Ca2+ augments the reactivation of reduced bovine pancreatic trypsin inhibitor |
651957 |
5.3.4.1 | Ca2+ |
can partially substitute for Mg2+ |
661641 |
5.3.4.1 | Ca2+ |
enzyme binds 19 mol Ca2+ per mol of protein with low affinity, which is reduced by increasing the ionic strength. Ca2+ induces conformational changes |
3073 |
5.3.4.1 | Ca2+ |
enzyme binds 23 mol Ca2+ at low affinity |
651957 |
5.3.4.1 | Ca2+ |
major calcium binding protein of the endoplasmic reticulum |
649629 |
5.3.4.1 | Ca2+ |
possibly bound at the C-terminal extension |
704927 |
5.3.4.1 | Ca2+ |
recombinant ECaST/PDI binds 26 mol of Ca2+/mol of protein with a Kd of 2.8 mM, 1-5 mM Ca2+ augments the reactivation of rBPTI |
651957 |
5.3.4.1 | Ca2+ |
the enzyme is a major calcium binding protein of the endoplasmic reticulum via acidic residues |
727573 |
5.3.4.1 | Co2+ |
can partially substitute for Mg2+ |
661641 |