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EC Number
Metals/Ions
Commentary
Reference
3.5.4.16
Zn2+
1 ion per active site
656261
3.5.4.16
Zn2+
absolutely required, e.g. for activity and reconstitution of the denatured enzyme, 1 Zn2+ bound per subunit of the decameric enzyme
655489
3.5.4.16
K+
activates
209550
,
209564
3.5.4.16
Li+
activates
209550
3.5.4.16
Mg2+
activates
209546
,
209566
3.5.4.16
Na+
activates
209550
3.5.4.16
Mn2+
at 2 mM Mn2+ is able to restore MptA activity to a higher level than Fe2+, Mn2+ enzyme is not inactivated by exposure to oxygen
685163
3.5.4.16
Zn2+
catalytically essential ion, complexed to 2 cysteine and 1 histidine residue
654607
3.5.4.16
Fe2+
dependent, contains 1 Fe2+ per protomer
685163
3.5.4.16
Zn2+
essential for activity, coordinated to a His-side chain of the active site
657176
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