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EC Number
Metals/Ions
Commentary
Reference
3.5.1.23
Ca2+
after EDTA treatment, Ca2+ reestablishes activity completely
171990
3.5.1.23
more
the ceramide synthesis activity is totally independent of stimulating cations
655998
3.5.1.23
more
112 kDa CDase from kidney is not activated by Ca2+
656010
3.5.1.23
Ca2+
slightly activates in a dose-dependent manner
656152
3.5.1.23
Ba2+
better activator than Mg2+
657260
3.5.1.23
Ca2+
Ca2+-dependent, better activator than Mg2+
657260
3.5.1.23
Mg2+
the maximum activity with Mg2+ is only 36% of that in presence of optimal Ca2+ or Ba2+ concentrations
657260
3.5.1.23
Ca2+
required
664159
,
711710
,
755558
3.5.1.23
Mg2+
can partially replace Ca2+
664159
3.5.1.23
Mn2+
can partially replace Ca2+
664159
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