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EC Number
Metals/Ions
Commentary
Reference
3.4.21.43
Ca2+
dependent on
732705
3.4.21.43
Ca2+
formation of the bimolecular complex C4b2a, i.e. C3 convertase
81407
3.4.21.43
Iodine
stabilization
81406
,
81407
,
81409
3.4.21.43
Li+
binds to complement component C2A
684068
3.4.21.43
Mg2+
formation of the bimolecular complex C4b2a, i.e. C3 convertase
81406
,
81407
3.4.21.43
Mg2+
required
732705
3.4.21.43
Mg2+
required during enzyme formation
683775
3.4.21.43
Mg2+
required for activity
754745
3.4.21.43
Mn2+
binds to complement component C2A
684068
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