EC Number   |
Metals/Ions |
Reference |
|---|
    2.7.8.7 | Mg2+ |
- |
645395, 645402, 645403, 645407, 645410, 761359 |
| 2.7.8.7 | Mn2+ |
- |
645395 |
| 2.7.8.7 | Mn2+ |
activates |
738930 |
| 2.7.8.7 | more |
Ca2+, Fe2+, Co2+ and Zn2+ are ineffective, inhibitory or both, at intermediate and high concentrations |
645395 |
| 2.7.8.7 | Mg2+ |
contains Mg2+ |
721646 |
| 2.7.8.7 | more |
CuSO4, CdCl2 and CrCl2 does not stimulate the reaction at any ceoncentration, trivalent metal cations such as FeCl3 or AlCl3 are ineffective |
486864 |
| 2.7.8.7 | Mg2+ |
dependent on |
723567, 738930, 739435 |
| 2.7.8.7 | Mg2+ |
dependent on, binding structure, overview. The edge strands beta4 and beta6 of the two beta-sheets provide the binding site for the CoA diphosphate and associated Mg2+ ion. The active site in Mtb-PptT is formed in the shallow cleft between the two domains, where CoA and Mg2+ are bound |
738932 |
| 2.7.8.7 | Mg2+ |
maximal activity at 0.025 mM |
486864 |
| 2.7.8.7 | more |
Mg2+ results in the highest activity among the divalent ions tested followed by Mn2+, while Ca2+ has no effect on the activity of the enzyme |
738930 |
