EC Number   |
Metals/Ions |
Reference |
|---|
   2.7.3.9 | Co2+ |
can substitute for Mg2+ |
642510 |
| 2.7.3.9 | Co2+ |
Km: 0.05 mM |
642508 |
| 2.7.3.9 | Mg2+ |
- |
642502, 642507, 642511, 672645 |
| 2.7.3.9 | Mg2+ |
50 mM used in assay conditions |
761389 |
| 2.7.3.9 | Mg2+ |
binding of phosphoenolpyruvate requires Mg2+ |
674583 |
| 2.7.3.9 | Mg2+ |
enzyme I of the PEP:sugar phosphotransferase system is regulated by a monomer-dimer equilibrium. A Mg2+-dependent autophosphorylation by phosphoenolpyruvate requires the homodimer. Physiological concentrations of phosphoenolpyruvate and Mg2+ increase, whereas pyruvate and Mg2+ decrease the amount of dimeric, active dephospho-enzyme I |
663326 |
| 2.7.3.9 | Mg2+ |
induces small conformational changes, large conformational changes with Mg2+ and phosphoenolpyruvate, swivelling mechanism, dimerization of the enzyme depends on its ligands |
674582 |
| 2.7.3.9 | Mg2+ |
Km: 0.53 mM |
642508 |
| 2.7.3.9 | Mg2+ |
necessary for dimerization, only the dimeric enzyme can be phosphorylated |
642505 |
| 2.7.3.9 | Mn2+ |
can substitute for Mg2+ |
642505 |
