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Information on EC 2.7.3.9 - phosphoenolpyruvate-protein phosphotransferase

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IUBMB Comments
Enzyme I of the phosphotransferase system (cf. EC 2.7.1.69 protein-Npi-phosphohistidine---sugar phosphotransferase). Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport. A similar reaction, where the protein is the enzyme EC 2.7.9.2 pyruvate, water dikinase, is part of the mechanism of that enzyme.
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The enzyme appears in viruses and cellular organisms
Synonyms
enzyme i, phosphoenolpyruvate:sugar phosphotransferase system, phosphoenolpyruvate-dependent phosphotransferase system, phosphoenolpyruvate:carbohydrate phosphotransferase system, phosphoenolpyruvate:glycose phosphotransferase system, phosphoenolpyruvate-dependent phosphotransferase, phosphoenolpyruvate:sugar phosphotransferase, enzyme i of the phosphotransferase system, phosphoenolpyruvate-protein phosphotransferase, phosphotransferase enzyme i, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
phosphoenolpyruvate + protein histidine = pyruvate + protein Npi-phospho-L-histidine
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phosphoenolpyruvate + protein histidine = pyruvate + protein N-pros-phosphohistidine
show the reaction diagram
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