EC Number   |
Metals/Ions |
Reference |
|---|
   2.7.10.1 | Ca2+ |
L-type Ca2+ channel activity is induced by enzyme activity regulating the Ca2+ flux and intracellular Ca2+ concentration, capacitative Ca2+ entry measurements using a fluorescent method |
661669 |
| 2.7.10.1 | Ca2+ |
ligand-binding induced dimerization enables transautophosphorylation of ErbB1 which results in enhanced intracellular cytoplasmic Ca2+ concentration activating calmodulin which reverses autoinhibition by net charge changes in the juxtamembranes |
662557 |
| 2.7.10.1 | Cd2+ |
can partially substitue Mg2+ |
490931 |
| 2.7.10.1 | Co2+ |
can partially substitue Mg2+ |
490931 |
| 2.7.10.1 | Cr3+ |
activates insulin receptor tyrosine phosphorylation in vivo |
661206 |
| 2.7.10.1 | hydrogen peroxide |
insulin-induced ROS production, limited exposure enhances insulin-induced autophosphorylation of the insulin receptor, while prolonged exposure impairs the action of insulin |
660729 |
| 2.7.10.1 | Mg2+ |
- |
489976, 490796, 490797, 490931, 661030, 661163, 661206, 661457, 661483 |
| 2.7.10.1 | Mg2+ |
as MgATP2- |
660921 |
| 2.7.10.1 | Mg2+ |
coordinates with Asp810 within the c-Kit DFG motif, overview |
662242 |
| 2.7.10.1 | Mg2+ |
dependent on, Mg2+ is the physiologic metal ion, other divalent cations are able to support nucleotide binding, but only Mn2+, Co2+, and Cd2+ can substitute Mg2+ in supporting the catalytic activity |
490931 |
