EC Number   |
Metals/Ions |
Reference |
|---|
   4.1.2.52 | Co2+ |
- |
702377 |
| 4.1.2.52 | Cu2+ |
0.5 mM chloride salt, 1% relative activity, with 4-hydroxy-2-oxopentanoate as substrate |
721601 |
| 4.1.2.52 | Co2+ |
0.5 mM chloride salt, 100% relative activity, with 4-hydroxy-2-oxopentanoate as substrate |
721601 |
| 4.1.2.52 | Ni2+ |
0.5 mM chloride salt, 11% relative activity, with 4-hydroxy-2-oxopentanoate as substrate |
721601 |
| 4.1.2.52 | Cd2+ |
0.5 mM chloride salt, 4% relative activity, with 4-hydroxy-2-oxopentanoate as substrate |
721601 |
| 4.1.2.52 | Mg2+ |
0.5 mM chloride salt, 49% relative activity, with 4-hydroxy-2-oxopentanoate as substrate |
721601 |
| 4.1.2.52 | Fe2+ |
0.5 mM chloride salt, 57% relative activity, with 4-hydroxy-2-oxopentanoate as substrate |
721601 |
| 4.1.2.52 | Zn2+ |
0.5 mM chloride salt, 73% relative activity, with 4-hydroxy-2-oxopentanoate as substrate |
721601 |
| 4.1.2.52 | Mn2+ |
0.5 mM chloride salt, 99% relative activity, with 4-hydroxy-2-oxopentanoate as substrate |
721601 |
| 4.1.2.52 | more |
H45A and H45Q mutant enzymes have 24fold and 69fold higher dissociation constants for Co2+ compared to the wild-type enzyme |
722258 |
