EC Number |
Inhibitors |
Structure |
---|
7.6.2.2 | (17beta)-N-([trans-4-[(6-amino-9H-purin-9-yl)methyl]cyclohexyl]methyl)-3-oxoandrost-4-ene-17-carboxamide |
daunorubicin accumulation is 99% of the accumulation in presence of 0.01 mM progesterone |
|
7.6.2.2 | (17beta)-N-[(2E)-4-(6-amino-9H-purin-9-yl)but-2-en-1-yl]-3-oxoandrost-4-ene-17-carboxamide |
daunorubicin accumulation is 72% of the accumulation in presence of 0.01 mM progesterone |
|
7.6.2.2 | (17beta)-N-[(2Z)-4-(6-amino-9H-purin-9-yl)but-2-en-1-yl]-3-oxoandrost-4-ene-17-carboxamide |
daunorubicin accumulation is 86% of the accumulation in presence of 0.01 mM progesterone |
|
7.6.2.2 | (17beta)-N-[4-(6-amino-9H-purin-9-yl)but-2-yn-1-yl]-3-oxoandrost-4-ene-17-carboxamide |
daunorubicin accumulation is 61% of the accumulation in presence of 0.01 mM progesterone |
|
7.6.2.2 | (17beta)-N-[4-(6-amino-9H-purin-9-yl)butyl]-3-oxoandrost-4-ene-17-carboxamide |
daunorubicin accumulation is 78% of the accumulation in presence of 0.01 mM progesterone |
|
7.6.2.2 | (17beta)-N-[4-[(6-amino-9H-purin-9-yl)methyl]benzyl]-3-oxoandrost-4-ene-17-carboxamide |
daunorubicin accumulation is 98% of the accumulation in presence of 0.01 mM progesterone |
|
7.6.2.2 | (17beta)-N-[6-(6-amino-9H-purin-9-yl)hexyl]-3-oxoandrost-4-ene-17-carboxamide |
daunorubicin accumulation is 111% of the accumulation in presence of 0.01 mM progesterone |
|
7.6.2.2 | (1beta,1'beta)-5-bromo-6,6',7,12-tetramethoxy-2-methylberbaman |
is an effectively and potential agent in reversing Pgp-mediated multidrug resistance by inhibiting the transport function and expression of Pgp |
|
7.6.2.2 | (1E)-1,5-bis[3,5-bis(methoxymethoxy)phenyl]-4,4-dibromopent-1-en-3-one |
58.7% inhibition at 0.01 mM |
|
7.6.2.2 | (1E)-1,5-bis[3,5-bis(methoxymethoxy)phenyl]-4,4-dichloropent-1-en-3-one |
51.5% inhibition at 0.01 mM |
|