EC Number   |
Inhibitors |
Structure |
|---|
    6.3.2.3 | 5,5'-dithiobis(2-nitrobenzoate) |
inhibition of ADP-ATP exchange reaction, no effect on tripeptide synthesis |
   |
| 6.3.2.3 | 5,5'-dithiobis(2-nitrobenzoate) |
- |
|
| 6.3.2.3 | 5,5'-dithiobis(2-nitrobenzoate) |
Cys289 is the only amino acid residue reactive with DTNB. Modification of Cys289 with DTNB results in complete loss of the catalytic activity |
|
| 6.3.2.3 | 7,8-dihydrofolate |
- |
|
| 6.3.2.3 | adenosine |
- |
|
| 6.3.2.3 | adenosine 5'-phosphosulfate |
slight |
|
| 6.3.2.3 | adenosine-5'-tetraphospho-5'-pyridoxal |
when incubated with an adenosine-5'-polyphospho-5'-pyridoxal or pyridoxal phosphate in the presence of Mg2+ and then reduced with sodium borohydride, it is most rapidly inactivated by adenosine-5'-tetraphospho-5'-pyridoxal, addition of either ATP or gamma-glutamylcysteine protects from inactivation |
|
| 6.3.2.3 | ADP |
strong |
|
| 6.3.2.3 | ADP |
- |
|
| 6.3.2.3 | ADP |
product inhibition |
|
