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EC Number
Inhibitors
Commentary
Structure
5.2.1.2
NEM
biphasic kinetics
5.2.1.2
NEM
-
5.2.1.2
iodoacetate
-
5.2.1.2
GSSG
-
5.2.1.2
NaBH4
inhibition in absence of substrate, increases activity in presence of substrate and GSH
5.2.1.2
Dichloroacetate
the sensitivity to the inhibitor varies between enzyme haplotypes. Three nonsynonymous single-nucleotide polymorphisms of GSTz1/MAAI show different activity toward dichloroacetate and certain other xenobiotic haloacids
5.2.1.2
S-Methylglutathione
-
5.2.1.2
maleylacetone
inhibits isomerization of 6-oxo-2(E),4(Z)-heptanedienoic acid into 6-oxo-2(Z),4(E)-heptanedienoic acid, and the reverse reaction
5.2.1.2
Dichloroacetic acid
DCA
5.2.1.2
N-Hexylmaleamic acid
noncompetitive towards GSH and maleylacetone
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