EC Number |
Inhibitors |
Structure |
---|
4.2.1.84 | (NH4)2S2O8 |
23% inhibition at 10 mM, 22% inhibition at 1 mM |
|
4.2.1.84 | 1,10-phenanthroline |
1 mM |
|
4.2.1.84 | 1,10-phenanthroline |
1-5 mM |
|
4.2.1.84 | 1,10-phenanthroline |
39% reduced activity at 1 mM |
|
4.2.1.84 | 1-butaneboronic acid |
competitive inhibitor, binds directly to the low-spin Co(III) ion in the active site of PtNHase; competitive inhibitor, binds directly to the low-spin Co(III) ion in the active site of PtNHase |
|
4.2.1.84 | 2,2'-dipyridyl |
1-5 mM |
|
4.2.1.84 | 2-mercaptoethanol |
- |
|
4.2.1.84 | 2-mercaptoethanol |
9% reduced activity at 1 mM |
|
4.2.1.84 | 2-Nitrophenol |
10 microM, 40-50% residual activity of NilFe, 90% residual activity of NilCo |
|
4.2.1.84 | 3-Cyanopyridine |
the soluble enzyme shows about 15% residual activity at 500 mM 3-cyanopyridine, NHase immobilized to EupergitC and cross-linked with 1-ethyl-3-(dimethylamino-propyl) carbodiimide shows approximately 50% reduction in 3-cyanopyridine inhibition (about 65% residual activity at 500 mM 3-cyanopyridine) |
|