EC Number   |
Inhibitors |
Structure |
|---|
   3.4.24.15 | (3-aminopropanoyl)-Pro-Pro-Gly-Phe-(3-aminopropanoic acid)-Pro-Phe-Arg |
no degradation by EC 3.4.24.15 |
   |
| 3.4.24.15 | (o-aminobenzoyl)-GFSIFRQ-(N-(2,4-dinitrophenyl)ethylenediamine) |
- |
|
| 3.4.24.15 | (o-aminobenzoyl)-GFSPPRQ-(N-(2,4-dinitrophenyl)ethylenediamine) |
- |
|
| 3.4.24.15 | 1,10-phenanthroline |
- |
|
| 3.4.24.15 | 1,4-dithiothreitol |
DTT inhibits both, TOP1 and TOP2. As with TOP1, both TOP2 monomeric and dimeric fractions are inhibited by the thiol-based reductant; DTT inhibits both, TOP1 and TOP2. As with TOP1, both TOP2 monomeric and dimeric fractions are inhibited by the thiol-based reductant |
|
| 3.4.24.15 | 2-mercaptoethanol |
- |
|
| 3.4.24.15 | 5-cyano-2-nitrothiobenzoate |
0.1 mM, 62% inhibition |
|
| 3.4.24.15 | ADP |
- |
|
| 3.4.24.15 | angiotensin I |
inhibits hydrolysis of 7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-D-Lys-(2,4-dinitrophenyl) |
|
| 3.4.24.15 | angiotensin II |
inhibits hydrolysis of 7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-D-Lys-(2,4-dinitrophenyl) |
|
