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EC Number
Inhibitors
Commentary
Structure
3.2.2.14
ATP
-
3.2.2.14
NAD+
greatly inhibited by intracellular levels of NAD+ and reduced NADH, addition of 1 mM NAD+, inhibition 73.2%
3.2.2.14
NADH
addition of 1 mM, inhibition 68.6%
3.2.2.14
NADP+
addition of 1 mM, inhibition 24%
3.2.2.14
Zn2+
1 mM
3.2.2.14
Cu2+
1 mM
3.2.2.14
EDTA
1 mM inhibits NMN hydrolysis by 30%
3.2.2.14
AMP
addition of 1.4 mM AMP, inhibition 92.5%
3.2.2.14
pyridoxal 5'-phosphate
addition of 1.4 mM, inhibition 8.8%
3.2.2.14
p-chloromercuribenzoate
50% inhibition at 3 mM
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