EC Number |
Inhibitors |
Structure |
---|
3.1.3.32 | more |
optimization of a rapid high-throughput screening method for detection of DNA 3'-phosphatases and their inhibitors, overview |
|
3.1.3.32 | more |
sensitivity to methyl methanesulfonate of all single and double mutant combinations of nth1, apn2, tdp1 and pnk1 |
|
3.1.3.32 | diphosphate |
no effect on 3'-phosphatase, inhibition of 5'-hydroxyl kinase |
|
3.1.3.32 | EDTA |
- |
|
3.1.3.32 | NaCl |
can replace Mg2+ at 50 mM, inhibitory at 250 mM |
|
3.1.3.32 | NaCl |
best stimulation at 100 mM, inhibitory above 200 mM |
|
3.1.3.32 | heparin |
- |
|
3.1.3.32 | heparin |
heparin exhibits an IC50 of 0.16 mg/ml |
|
3.1.3.32 | SO42- |
5'-hydroxyl kinase, little effect on 3'-phosphatase |
|
3.1.3.32 | PO43- |
5'-hydroxyl kinase, little effect on 3'-phosphatase |
|