EC Number |
Inhibitors |
Structure |
---|
3.1.1.63 | all-trans-retinyl bromoacetate |
0.05 mM 50% inhibition |
|
3.1.1.63 | all-trans-retinyl palmitate |
weak inhibition |
|
3.1.1.63 | more |
the distinctive apparent inhibition constants for NEM-induced inhibition of 11-cis retinyl-palmitate hydrolase and the all-trans-retinyl-palmitate hydrolase activity suggest a fundamental difference in the amino acid composition at the active site of the enzyme(s) |
|
3.1.1.63 | NEM |
inhibits all-trans retinyl-palmitate hydrolase and 11-cis-retinyl-palmitate hydrolase activity of the liver enzyme, inhibits all-trans-retinyl-palmitate hydrolase activity of the pigment epithelium, 1-cis-retinyl-palmitate hydrolase activity of the pigment epithelium is unaffected |
|
3.1.1.63 | triolein |
inhibits all-trans retinyl-palmitate hydrolase and 11-cis-retinyl-palmitate hydrolase activity of the liver enzyme, inhibits all-trans-retinyl-palmitate hydrolase activity of the pigment epithelium, 1-cis-retinyl-palmitate hydrolase activity of the pigment epithelium is unaffected |
|