EC Number   |
Inhibitors |
Structure |
|---|
   3.1.1.25 | 2-hydroxyquinoline |
- |
   |
| 3.1.1.25 | 2-hydroxyquinoline |
specific inhibitor |
|
| 3.1.1.25 | 8-hydroxyquinoline |
at 2 mM, 50% residual activity |
|
| 3.1.1.25 | Ag+ |
33.2% residual activity at 1 mM |
|
| 3.1.1.25 | Al3+ |
22.4% residual activity at 1 mM |
|
| 3.1.1.25 | AlCl3 |
at 2 mM, 66% residual activity |
|
| 3.1.1.25 | ascorbate |
ascorbate/Cu2+ system is the most potent in inactivating the lactonase activity (by 90%). Cu2+ remarkably enhances the inactivation in the presence of ascorbate. Ascorbate/Cu2+ (0.5 mM/0.001 mM) system shows ca. 95% inactivation. Ascorbate/Cu2+-mediated inactivation of lactonase activity is prevented by catalase (90%), oleic acid (73% at 0.01 mM) and dioleoylphosphatidylcholine (68% at 0.1 mM). Ascorbate/Fe2+ (0.5 mM/0.002 mM) system shows 20% inactivation |
|
| 3.1.1.25 | CdCl2 |
77.7% residual activity after 24 h in the presence of 0.02 mg/ml CdCl2 |
|
| 3.1.1.25 | Co2+ |
10.7% residual activity at 1 mM |
|
| 3.1.1.25 | Cu+ |
13.6% residual activity at 1 mM |
|
