EC Number |
Inhibitors |
Structure |
---|
2.4.1.34 | (1R,3R,6aS,7R,8R,10bR,12aR)-1,6a,8,10a-tetramethyl-8-[(2R)-3-methylbutan-2-yl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]-3-[5-(pyridin-4-yl)-1H-1,2,4-triazol-1-yl]-1,3,4,6,6a,7,8,9,10,10a,10b,11,12,12a-tetradecahydro-2H-1,4a-(methanooxymethano)chrysene-7-carboxylic acid |
IC50: 19 ng/ml, pH and temperature not specified in the publication |
|
2.4.1.34 | (1R,3R,6aS,7R,8R,10bR,12aR)-1,6a,8,10a-tetramethyl-8-[(2R)-3-methylbutan-2-yl]-2-[[(2R)-2-methylpyrrolidin-2-yl]methoxy]-3-[5-(pyridin-4-yl)-1H-1,2,4-triazol-1-yl]-1,3,4,6,6a,7,8,9,10,10a,10b,11,12,12a-tetradecahydro-2H-1,4a-(methanooxymethano)chrysene-7-carboxylic acid |
IC50: 4 ng/ml, pH and temperature not specified in the publication |
|
2.4.1.34 | (1R,3R,6aS,7R,8R,10bR,12aR)-1,6a,8,10a-tetramethyl-8-[(2R)-3-methylbutan-2-yl]-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-3-[5-(pyridin-4-yl)-1H-1,2,4-triazol-1-yl]-1,3,4,6,6a,7,8,9,10,10a,10b,11,12,12a-tetradecahydro-2H-1,4a-(methanooxymethano)chrysene-7-carboxylic acid |
IC50: 61 ng/ml, pH and temperature not specified in the publication |
|
2.4.1.34 | (1R,3R,6aS,7R,8R,10bR,12aR)-1,6a,8,10a-tetramethyl-8-[(2R)-3-methylbutan-2-yl]-3-[5-(pyridin-4-yl)-1H-1,2,4-triazol-1-yl]-2-[(2R)-pyrrolidin-2-ylmethoxy]-1,3,4,6,6a,7,8,9,10,10a,10b,11,12,12a-tetradecahydro-2H-1,4a-(methanooxymethano)chrysene-7-carboxylic acid |
IC50: 22 ng/ml, pH and temperature not specified in the publication |
|
2.4.1.34 | (1R,3R,6aS,7R,8R,10bR,12aR)-1,6a,8,10a-tetramethyl-8-[(2R)-3-methylbutan-2-yl]-3-[5-(pyridin-4-yl)-1H-1,2,4-triazol-1-yl]-2-[(2S)-pyrrolidin-2-ylmethoxy]-1,3,4,6,6a,7,8,9,10,10a,10b,11,12,12a-tetradecahydro-2H-1,4a-(methanooxymethano)chrysene-7-carboxylic acid |
IC50: 18 ng/ml, pH and temperature not specified in the publication |
|
2.4.1.34 | (1R,3R,6aS,7R,8R,10bR,12aR)-2-[[(2R)-1,2-dimethylpyrrolidin-2-yl]methoxy]-1,6a,8,10a-tetramethyl-8-[(2R)-3-methylbutan-2-yl]-3-[5-(pyridin-4-yl)-1H-1,2,4-triazol-1-yl]-1,3,4,6,6a,7,8,9,10,10a,10b,11,12,12a-tetradecahydro-2H-1,4a-(methanooxymethano)chrysene-7-carboxylic acid |
IC50: 6.4 ng/ml, pH and temperature not specified in the publication |
|
2.4.1.34 | (1R,6aS,7R,8R,10bR,12aR)-1,6a,8,10a-tetramethyl-8-[(2R)-3-methylbutan-2-yl]-3-[5-(pyridin-4-yl)-1H-1,2,4-triazol-1-yl]-2-[[(2R)-2,3,3-trimethyl-2-(methylamino)butyl]oxy]-1,3,4,6,6a,7,8,9,10,10a,10b,11,12,12a-tetradecahydro-2H-1,4a-(methanooxymethano)chrysene-7-carboxylic acid |
IC50: 2 ng/ml, pH and temperature not specified in the publication |
|
2.4.1.34 | (2,6-difluoro-phenyl)-carbamic acid 3-(4-benzothiazol-2-yl-piperazine-1-yl)-propyl ester |
The piperazine propanol derivative GS1578 was identified as a potent inhibitor against 1,3-beta-D-glucan synthase, IC50: 0.16 microM. |
|
2.4.1.34 | 1,2-Bis(O-aminophenoxy)ethane-N,N,N',N'-tetraacetate |
- |
|
2.4.1.34 | 5-azido-UDP-glucose |
- |
|