EC Number |
Inhibitors |
Structure |
---|
1.2.7.4 | more |
dimethylglyoxime is no inhibitor, formaldehyde and acetaldehyde does not inactivate the enzyme; not inhibited by 20 mM formaldehyde or acetaldehyde |
|
1.2.7.4 | more |
pyruvate and ATP have no effect |
|
1.2.7.4 | more |
not affected by propyl iodide, methyl iodide, carbon tetrachloride,or metal chelators; not inhibited by propyl iodide, methyl iodide, carbon tetrachloride, EDTA or nitrilotriacetate |
|
1.2.7.4 | more |
phenylglyoxal, methylglyoxal, butanedione, mersalyl acid, methyl iodide, 5,5'-dithiobis (2-nitrobenzoate) and sodium dithionite inhibits the exchange reaction between CO and acetyl-CoA |
|
1.2.7.4 | more |
inhibition data are interpreted in terms of two binding sites for CO on CO dehydrogenase |
|
1.2.7.4 | O2 |
- |
|
1.2.7.4 | D-glucose |
partially inhibited by incubation with 0.5 mM exogenous D-glucose |
|
1.2.7.4 | 1,10-phenanthroline |
1 mM, inactivates CO/acetyl-CoA exchange activity completely but has no effect on CO oxidation |
|
1.2.7.4 | PCMB |
- |
|
1.2.7.4 | cyanide |
potent inhibitor |
|