EC Number   |
Inhibitors |
Structure |
|---|
  1.14.14.178 | (2RS,4RS)-1-[4-propyl-2-(4-trifluoromethylphenyl)-1,3-dioxolan-2-ylmethyl]-1H-1,2,4-triazole |
DWF4 is the target site of Brz220 in Arabidopsis. Arabidopsis thaliana treated with 2RS,4RS-1-[4-propyl-2-(4-trifluoromethylphenyl)-1,3-dioxane-2-ylmethyl]-1H-1,2,4-triazole shows a dwarf phenotype |
   |
| 1.14.14.178 | 2,22,25-trideoxyecdysone |
competitive |
|
| 1.14.14.178 | 2-deoxyecdysone |
competitive |
|
| 1.14.14.178 | bitertanol |
i.e. 2,3,3-trimethyl-1-biphenyl4-yloxy-1-(1H-1,2,4-triazol-1-yl)butan-2-ol, Kd value is 0.0467 mM |
|
| 1.14.14.178 | brassinazole |
addition of brassinazole to the DWF4 protein induces a type II absorbance shift of the heme Soret band from 416 to 421 nm indicative of direct coordination of the triazole group of the brassinazole to the heme iron of DWF4. Kd value for brassinazole is 0.000001 M |
|
| 1.14.14.178 | Brz117 |
i.e. 4-(3-methoxyphenyl)-2-phenyl-3-(1H-1,2,4-triazol-1-yl)butan-2-ol, Kd value is 0.0117 mM |
|
| 1.14.14.178 | difenoconazole |
Kd value is 0.0453 mM |
|
| 1.14.14.178 | ecdysone |
competitive |
|
| 1.14.14.178 | triadimefon |
- |
|
