EC Number |
Inhibitors |
Structure |
---|
3.5.99.7 | 1-amino-2,2-difluorocyclopropane-1-carboxylic acid |
rac-DFACC, chemical synthesis, overview. Mechanism of decomposition and inhibition of 1-aminocyclopropane-1-carboxylic acid deaminase, and Michaelis-Menten kinetics. DFACC is unstable under near-physiological conditions where it primarily decomposes via specific-base catalysis to 3-fluoro-2-oxobut-3-enoic acid. Different decomposotion mechanisms are described. Upon incubation with ACC deaminase, DFACC is a slow-dissociating inhibitor of ACC deaminase with submicromolar affinity |
|
3.5.99.7 | 1-amino-2-methylenecyclopopropane-1-carboxylic acid |
irreversible |
|
3.5.99.7 | 1-aminocyclopropanephosphonate |
- |
|
3.5.99.7 | 5,5'-dithiobis(2-nitrobenzoic acid) |
- |
|
3.5.99.7 | aminooxyacetic acid |
0.005-1 mM, enzymatic activity is progressively inhibited as the aminooxyacetic acid concentration is increased |
|
3.5.99.7 | beta-chloro-Ala |
- |
|
3.5.99.7 | beta-chloro-Ala |
mechanism-based inhibition |
|
3.5.99.7 | beta-fluoro-D-Ala |
- |
|
3.5.99.7 | cyclohexylhydrazine |
- |
|
3.5.99.7 | D-Ala |
- |
|