EC Number |
Inhibitors |
Structure |
---|
3.2.2.14 | dCMP |
effective inhibition in presence of 1 mM GTP, noncompetitive inhibitor |
|
3.2.2.14 | desamido-NAD+ |
addition of 1 mM, inhibition 66.6% |
|
3.2.2.14 | dGMP |
effective inhibition in presence of 1 mM GTP, noncompetitive inhibitor |
|
3.2.2.14 | EDTA |
1 mM inhibits NMN hydrolysis by 30% |
|
3.2.2.14 | GMP |
addition of 1.4 mM GMP, inhibition 89.4% |
|
3.2.2.14 | GMP |
effective inhibition in presence of 1 mM GTP |
|
3.2.2.14 | guanosine |
addition of 1.4 mM, inhibition 44.6% |
|
3.2.2.14 | N-ethylmaleimide |
50% inhibition at 80 mM |
|
3.2.2.14 | NAD+ |
greatly inhibited by intracellular levels of NAD+ and reduced NADH, addition of 1 mM NAD+, inhibition 73.2% |
|
3.2.2.14 | NADH |
addition of 1 mM, inhibition 68.6% |
|